That mistake came from Mile Svilar, who made history in the match by becoming youngest-ever goalkeeper at 18 years and 52 days but saw his costly error - a positional mistake that saw him drift across the line and into the goal with the ball in his hands - hand Marcus Rashford a goal and Manchester United the match.
"Not that I read it a lot, but sometimes when I read the press, not only English but Portuguese, I feel that sometimes defending properly is seen as a crime but it is not", he told a press conference.
"I think the way to do it is to ignore the players that are injured, is to focus on the players that are available.it is to give confidence to the players that are available".
Mourinho says he's not like other managers who moan about injuries.
"Ibrahimovic, Pogba, Fellaini, Marcos Rojo, I can cry but I don't, so we do it with what we have".
Marcos Rojo and Zlatan Ibrahimovic continue their comeback from serious knee ligament injuries, while midfielders Michael Carrick, Paul Pogba and Marouane Fellaini are now out injured. We brought a kid, like Benfica does, because I don't have another solution.
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"But the Premier League is a different story".
"But, again, you know, 12 matches, 10 victories, two draws, nine clean sheets".
"I don't think there is an answer for that, I'm not in conditions to answer to that because there is nothing to answer, I have a contract and that's it".
Mourinho said: "Rashford, I thought it was cramps because he was running so much, it was about muscular fatigue, but he felt something in his knee but to me it doesn't look a big thing".
"We had control, some difficulties in the first 30 minutes but then we controlled the pitch".
"I will support them for the rest of my life and they will have a special place in my heart, but in the Champions League I hope we can take points from them". It was not magic, but it was a solid performance.